GRAM-NEGATIVE BACTERIAL PNEUMONIA WITH SECONDARY ASPERGILLOSIS IN AN AIDS PATIENT
GRAM-NEGATIVE BACTERIAL PNEUMONIA WITH SECONDARY ASPERGILLOSIS IN AN AIDS PATIENT
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DOI：
10.1007/bf01649459
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发表时间：
1991-11-15
期刊：
影响因子：
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通讯作者：
HEINE, M
中科院分区：
文献类型：
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作者：
BONATZ, K;WEISS, A;HEINE, M
一名40岁的HIV感染女性患者因尿路感染接受抗生素治疗。 经过初步成功的治疗和无菌期后，她发展为感染性休克和成人呼吸窘迫综合征（ARDS）的肺炎。 尽管经过重症监护和呼吸机治疗及呼气末正压通气（PEEP），患者仍死于感染性中毒性休克。 尸检结果显示复发性革兰氏阴性细菌性肺炎（形态学上与克雷伯菌肺炎相符）和继发性侵袭性曲霉菌病。 这些不寻常的并发症的艾滋病的发病机制和流行病学进行了讨论。
A 40-year-old, HIV-infected female patient received antibiotic treatment for a urinary tract infection. After the initial success of therapy and a symptom-free period, she developed pneumonia with septic shock and adult respiratory distress syndrome (ARDS). In spite of intensive care and respirator therapy with positive end-expiratory pressure (PEEP), she died of infectious toxic shock. Autopsy findings showed relapsing, gram-negative, bacterial pneumonia (morphologically compatible with Klebsiella pneumonia) and secondary, invasive aspergillosis. The pathogenesis and epidemiology of these unusual complications of AIDS are discussed.