Antioxidant Activity of Fungus Comb Extracts Isolated from Indo-Malayan Termite Macrotermes gilvus Hagen (Isoptera: Termitidae)
Antioxidant Activity of Fungus Comb Extracts Isolated from Indo-Malayan Termite Macrotermes gilvus Hagen (Isoptera: Termitidae)
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从印度-马来白蚁 Macrotermes gilvus Hagen（等翅目：白蚁科）分离的真菌梳提取物的抗氧化活性
DOI：
10.22146/ijc.77227
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发表时间：
2022
影响因子：
0.9
通讯作者：
L. Witasari
中科院分区：
文献类型：
--
作者：
Y. Rachmayanti;D. Firmansyah;Reza Ro'isatul Umma;D. M. Hertanto;I. Sudiana;D. Santoso;D. Nandika;L. Karlinasari;A. Arinana;Irmanida Batubara;L. Witasari
印度尼西亚白蚁是最丰富的生物资源之一，因为它们在印度尼西亚大陆具有非常高的物种多样性（300种）和广泛的地理分布。然而，其作为生物活性化合物来源的潜力尚未得到充分开发。印度尼西亚特有的白蚁亚科之一，大白蚁亚科（等翅目：白蚁科），具有以真菌结节形式的食物来源，真菌结节在白蚁巢中以特定结构生长和传播，其形状像哺乳动物的大脑，称为真菌梳，其可能用作生物活性化合物的来源。本研究的目的是分析潜在的真菌梳从印尼Macrotermitinae亚科物种作为抗氧化剂的来源。以DPPH·（1，1-二苯基-2-苦肼基）和ABTS·+（2，2 ′-连氮基-二-[3-乙基苯并噻唑啉磺酸盐]）自由基为自由基，研究了真菌冠（EFC）正己烷提取物、乙酸乙酯提取物、甲醇提取物和水提取物的抗氧化活性。结果表明，抗氧化活性以甲醇提取物最高，其次为乙酸乙酯提取物，其IC 50值分别为0.6 mg/mL和0.75 mg/mL。TEAC（Trolox等效抗氧化能力）分析证实了甲醇提取物的高抗氧化活性。
Indonesian termites are one of the wealthiest biological resources considering their very high species diversity (300 species) and extensive geographical distribution in the Indonesian mainland. However, its potential as a source of bioactive compounds has not been fully explored. One of the endemic termite sub-families of Indonesian, Macrotermitinae (Isoptera: Termitidae), has a food source in the form of fungal nodules that grow and spread in a particular structure in the termite nest that is shaped like a mammalian brain called a fungus comb, which likely serves as a source of bioactive compounds. This study aims to analyze the potential of fungus comb from an Indonesian Macrotermitinae sub-family species as a source of antioxidants. Antioxidant activity was tested on four different extracts of fungus comb (EFC), namely hexane extract, ethyl acetate extract, methanol extract and water extract, using DPPH• (1,1-diphenyl-2-picrylhydrazyl) and ABTS•+ (2,2′-azino-di-[3-ethylbenzthiazolinesulphonate]) radicals. The results showed that the highest antioxidant activity was found in methanol extract, followed by ethyl acetate extract with IC50 values of 0.6 mg/mL and 0.75 mg/mL, respectively. TEAC (Trolox equivalent antioxidant capacity) analysis confirmed the high antioxidant activity of methanol extract.
DOI：
10.1098/rspb.2018.2076
发表时间：
2019-01-23
影响因子：
4.7
作者：
Evangelista, Dominic A.;Wipfler, Benjamin;Simon, Sabrina
通讯作者：
Simon, Sabrina