Premovement activity of the pre-supplementary motor area and the readiness for action: Studies of time-resolved event-related functional MRI
Premovement activity of the pre-supplementary motor area and the readiness for action: Studies of time-resolved event-related functional MRI
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DOI：
10.1016/j.humov.2005.10.001
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发表时间：
2005-10-01
影响因子：
2.1
通讯作者：
Moser, E
中科院分区：
文献类型：
--
作者：
Cunnington, R;Windischberger, C;Moser, E
辅助运动区(SMA)被认为在自主运动的准备和组织中起着重要作用。很早就知道，在自愿自主运动之前，大脑皮层活动开始增加，最高可达2 S。在EEG中测量到的这种不断增加的运动前活动被称为Bereitschaft斑点电位或准备就绪电位。使用事件相关和时间分辨功能MRI技术的现代脑功能成像方法开始揭示SMA，特别是更前部的SMA前活动在运动前活动中与行动准备相关的作用。在这篇文章中，我们回顾了最近的研究，使用事件相关的时间分辨fMRI方法来检查在动作的准备、准备和执行过程中SMA内的激活变化的时间进程。这些研究表明，前SMA在编码或表征我们自己的自发动作之前的动作、在运动想象过程中以及从对他人动作的观察中起着共同的作用。我们建议前SMA生成并编码运动表示，然后将其保持在准备行动的状态。(C)2005 Elsevier B.V.保留所有权利。
The supplementary motor area (SMA) is thought to play in important role in the preparation and organisation of voluntary movement. It has long been known that cortical activity begins to increase up to 2 s prior to voluntary self-initiated movement. This increasing premovement activity measured in EEG is known as the Bereitschaftspotential or readiness potential. Modern functional brain imaging methods, using event-related and time-resolved functional MRI techniques, are beginning to reveal the role of the SMA, and in particular the more anterior pre-SMA, in premovement activity associated with the readiness for action. In this paper we review recent studies using event-related time-resolved fMRI methods to examine the time-course of activation changes within the SMA throughout the preparation, readiness and execution of action. These studies suggest that the preSMA plays a common role in encoding or representing actions prior to our own voluntary self-initiated movements, during motor imagery, and from the observation of others' actions. We suggest that the pre-SMA generates and encodes motor representations which are then maintained in readiness for action. (c) 2005 Elsevier B.V. All rights reserved.