Residual sight-threatening lesions in leprosy patients completing multidrug therapy and sulphone monotherapy.

Residual sight-threatening lesions in leprosy patients completing multidrug therapy and sulphone monotherapy.
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完成多药治疗和砜单药治疗的麻风患者残留的威胁视力的病变。

DOI:
10.5935/0305-7518.19910005
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发表时间:
1991
期刊:
影响因子:
0.6
通讯作者:
HE Tjffytc
HE Tjffytc
中科院分区:
医学4区
文献类型:
--
作者:
HE Tjffytc

文献摘要

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对来自23个地区麻风病人群横截面的眼部发现的标准化调查数据进行了分析。结果显示,24.3%完成多药治疗的患者和32.9%完成磺胺砜单药治疗的患者存在持续的眼部问题,这些问题可能导致失明或严重的视力损害。眼部并发症多累及眼睑、角膜和前膜束,但有相当比例的患者存在白内障威胁视力。如果不加监督,这些病人中的许多人会出现本可以避免的严重视力问题。重要的是,完成麻风病的全身治疗不应被视为眼睛安全的保证,在患者被归类为“治愈”后,应长期继续进行定期的眼部监测。
An analysis of data derived from standardized surveys of the ocular findings in cross-sections of the leprosy population in 23 areas is presented. It shows that 24.3% of the patients completing multidrug therapy and 32.9% of those completing sulphone monotherapy have on-going eye problems which have the potential to lead to blindness or severe visual impairment. Most of the ocular complications involve the lids, cornea and anterior uveal tract, but a significant proportion of patients had cataract threatening vision. If left unsupervised, many of these patients will develop major visual problems which could have been avoided. It is important that completion of systemic leprosy therapy should not be regarded as a guarantee that the eyes are safe, and that regular ocular supervision should be continued long after the patient has been classified as 'cured'.