Direct asymmetric Michael addition of phthalide derivatives to chalcones
Direct asymmetric Michael addition of phthalide derivatives to chalcones
复制标题
苯酞衍生物与查耳酮的直接不对称迈克尔加成
DOI:
10.1016/j.tetlet.2013.07.108
复制
发表时间:
2013-09-18
影响因子:
1.8
通讯作者:
Lu, Yixin
中科院分区:
文献类型:
--
作者:
Luo, Jie;Jiang, Chunhui;Lu, Yixin
The Michael addition of phthalides to chalcones employing a quinidine-derived thiourea catalyst Q-1 has been developed. The reported method led to the synthesis of 3,3-disubstituted phthalide derivatives in excellent yields, with excellent diastereo- and enantioselectivities. (C) 2013 Published by Elsevier Ltd.