Direct asymmetric Michael addition of phthalide derivatives to chalcones

Direct asymmetric Michael addition of phthalide derivatives to chalcones
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苯酞衍生物与查耳酮的直接不对称迈克尔加成

DOI:
10.1016/j.tetlet.2013.07.108
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发表时间:
2013-09-18
影响因子:
1.8
通讯作者:
Lu, Yixin
Lu, Yixin
中科院分区:
化学4区
文献类型:
--
作者:
Luo, Jie;Jiang, Chunhui;Lu, Yixin

文献摘要

被引文献

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The Michael addition of phthalides to chalcones employing a quinidine-derived thiourea catalyst Q-1 has been developed. The reported method led to the synthesis of 3,3-disubstituted phthalide derivatives in excellent yields, with excellent diastereo- and enantioselectivities. (C) 2013 Published by Elsevier Ltd.