Circasemidian 12 h cycle of slow wave sleep under constant darkness
Circasemidian 12 h cycle of slow wave sleep under constant darkness
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DOI：
10.1016/s1388-2457(02)00168-2
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发表时间：
2002-09-01
影响因子：
4.7
通讯作者：
Hori, T
中科院分区：
文献类型：
--
作者：
Hayashi, M;Morikawa, T;Hori, T
目的：午睡是一种普遍存在的现象。本研究旨在验证Broughton的假说(睡眠和警觉：午睡的时间生物学、行为学和医学方面。纽约，NY：乌鸦出版社，1989。当天下午的睡眠倾向可能反映了慢波睡眠(SWS)的大约12h周期。方法：9名21-27岁的受试者在持续黑暗(0勒克斯)下独处72h，不进行社交接触，允许他们自由睡眠和进食。结果：总睡眠时间(TST)占总睡眠时间(TST)的41.6h(57.9%)，且随时间递减。TST的减少与睡眠阶段2和快速眼动睡眠(REM)的减少有关。SWS的数量在各天之间没有显著变化。SWS存在昼夜节律(1周/天)和昼夜节律(2周/天)周期。对总变异的贡献率分别为13.9%和11.1%。夜间睡眠门前9~10h和夜间睡眠门后15~16h出现与白天相对应的SWS。此外，短暂性睡眠的数量与睡眠前的清醒时间(r=0.332)和快速眼动睡眠前(r=-0.236)之间存在微弱但显著的相关性。结论：短暂性睡眠短暂性睡眠的发生可能不仅是作为先前觉醒的一种功能，而且是一种昼夜节律功能。(C)2002爱思唯尔科学爱尔兰有限公司。保留所有权利。
Objectives: Afternoon sleepiness is a widespread phenomenon. The present study aimed to test Broughton's hypothesis (Sleep and alertness: chronobiological, behavioral, and medical aspects of napping. New York, NY: Raven Press, 1989. p. 71-98) that afternoon sleep propensity might reflect the circasemidian 12 h cycle of slow wave sleep (SWS).Methods: Nine subjects (21-27 year) stayed alone under constant darkness (0 lux) without social contact for 72 h. They were allowed to sleep and eat freely. Their polysomnograms during 72 h of constant darkness were analyzed.Results: The total sleep time (TST) accounted for 41.6 h (57.9%) of the 72 h and decreased progressively as a function of time. The reduction in TST was dependent on the decrease in sleep stage 2 and rapid eye movement (REM) sleep. The amount of SWS did not significantly change among the days. The circadian (1 cycle/day) and circasemidian (2 cycles/day) cycles were observed in SWS. Those accounted for 13.9 and 11.1% of the total variance, respectively. SWS during the time corresponding to daytime occurred 9-10 h before and 15-16 h after the nocturnal sleep gate. In addition, weak but significant correlations were observed between the amounts of SWS and the waking time before the sleep episodes (r = 0.332) and prior REM sleep (r = -0.236).Conclusions: The present findings suggest that SWS might occur not only always in a homeostatic manner as a function of prior wakefulness, but also as a circasemidian rhythmic function. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.