Characterization of indeterminate (lipid-poor) adrenal masses:: Use of washout characteristics at contrast-enhanced CT
Characterization of indeterminate (lipid-poor) adrenal masses:: Use of washout characteristics at contrast-enhanced CT
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DOI：
10.1148/radiology.217.3.r00dc29798
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发表时间：
2000-12-01
期刊：
影响因子：
19.7
通讯作者：
Mueller, PR
中科院分区：
文献类型：
--
作者：
Peña, CS;Boland, GWL;Mueller, PR
目得：为了确定计算机断层扫描（CT）和对比剂增强和非增强CT扫描的衰减测量是否可用于描述肾上腺肿块，特别是通过使用对比剂增强CT的肾上腺洗脱特征来描述这些病变。（49名男性，37名女性;年龄范围，29-86岁;平均年龄，72岁）在对比增强CT中描绘的101个肾上腺病变进行了延迟（平均，9分钟）增强扫描。78例患者还接受了非增强CT检查。良性病变平均直径为2.1 cm（范围：1.0-4.2 cm）;恶性病变平均直径为2.3 cm（范围：1.0-4.1 cm）。感兴趣区域在非增强、动态增强和延迟增强CT中获得测量值，并用于计算相对洗脱百分比，如下所示：1 -结果：101个病灶中，99个病灶在延迟扫描中被正确定性为良性或恶性，相对洗脱阈值为50%;良性病变表现出超过50%的洗脱;恶性病变，小于50%的洗脱。两个良性病变表现出小于50%洗脱的特点是良性的，通过使用传统的CT.CONCLUSION：计算相对百分比洗脱的动态和延迟增强CT扫描可能会导致一个高度特异性的测试肾上腺病变的表征，减少需要，并可能导致，后续成像或活检。
PURPOSE: To determine whether computed tomographic (CT) scans and attenuation measurements on contrast material-enhanced and nonenhanced CT scans could be used to characterize adrenal masses, in particular, to characterize these lesions by using adrenal washout characteristics at contrast-enhanced CT.MATERIALS AND METHODS: Eighty-six patients (49 men, 37 women; age range, 29-86 years; mean age, 72 years) with 101 adrenal lesions depicted at contrast-enhanced CT underwent delayed (mean, 9 minutes) enhanced scanning. Seventy-eight patients also underwent nonenhanced CT. Mean diameter of the benign lesions was 2.1 cm (range, 1.0-4.2 cm); mean diameter of the malignant lesions was 2.3 cm (range, 1.0-4.1 cm). Region-of-interest. measurements were obtained at nonenhanced, dynamic enhanced, and delayed enhanced CT and were used to calculate a relative percentage washout as follows: 1 - (Hounsfield unit measurement on delayed image divided by Hounsfield unit measurement on dynamic image) x 100%.RESULTS: Ninety-nine of 101 lesions were correctly characterized as benign or malignant with a relative percentage washout threshold of 50% on delayed scans; benign lesions demonstrated more than 50% washout; and malignant lesions, less than 50% washout. Two benign lesions demonstrating less than 50% washout were characterized as benign by using conventional CT.CONCLUSION: Calculation of relative percentage washout on dynamic and delayed enhanced CT scans may lead to a highly specific test for adrenal lesion characterization, reduce the need for, and possibly obviate, follow-up imaging or biopsy.