ECHOGRAPHIC FEATURES OF THE VOGT-KOYANAGI-HARADA SYNDROME
ECHOGRAPHIC FEATURES OF THE VOGT-KOYANAGI-HARADA SYNDROME
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DOI：
10.1001/archopht.1990.01070120069031
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发表时间：
1990-10-01
影响因子：
--
通讯作者：
RAO, NA
中科院分区：
文献类型：
--
作者：
FORSTER, DJ;CANO, MR;RAO, NA
Vogt-Koyanagi-Harada（VKH）综合征是一种伴有中枢神经系统和皮肤科表现的双侧全葡萄膜炎。诊断是基于临床和血管造影的结果，但一些特征性的功能可能是不存在或难以可视化的存在不透明的媒体。使用标准化超声心动图（标准化A-扫描和接触B-扫描超声心动图），我们检查了9例VKH综合征的明确媒体和临床证据。一致的回声检查结果包括：（1）弥漫性、低至中等反射的后部脉络膜增厚;（2）浆液性视网膜脱离，位于前部或后极部;（3）轻度玻璃体混浊，无后玻璃体脱离;（4）后部巩膜和/或巩膜外层增厚。这些发现的解决与全身皮质类固醇治疗。标准化超声心动图应被认为是VKH综合征的重要诊断工具，尤其是当眼底显影不佳或临床表现不典型时。
Vogt-Koyanagi-Harada (VKH) syndrome represents a spectrum of bilateral panuveitis with associated central nervous system and dermatologic manifestations. The diagnosis is based on clinical and angiographic findings, but some of the characteristic features may be either absent or difficult to visualize in the presence of opaque media. With the use of standardized echography (standardized A-scan and contact B-scan echography), we examined nine patients with clear media and clinical evidence of VKH syndrome. Consistent echographic findings included (1) diffuse, low to medium reflective thickening of the choroid posteriorly; (2) serous retinal detachment, located inferiorly or in the posterior pole; (3) mild vitreous opacities with no posterior vitreous detachment; and (4) thickening of the sclera and/or episclera posteriorly. Resolution of these findings occurred with systemic corticosteroid therapy. Standardized echography should be considered an important diagnostic tool in VKH syndrome, especially when visualization of the fundus is poor or when clinical presentation is atypical.