STROKE ASSOCIATED WITH METHAMPHETAMINE INHALATION
STROKE ASSOCIATED WITH METHAMPHETAMINE INHALATION
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DOI：
10.1159/000117002
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发表时间：
1994-01-01
影响因子：
2.4
通讯作者：
HU, HH
中科院分区：
文献类型：
--
作者：
YEN, DJ;WANG, SJ;HU, HH
在过去两年中收集了7名因吸入甲基苯丙胺而发生中风的患者(均为男性，平均年龄32岁，范围为17-47岁)。与口服或静脉注射滥用者一样，我们的患者有更多的出血性(n=5)比缺血性中风(n=2)。脑出血3例为脑叶出血，1例为尾状脑出血，1例为壳核出血，两者均位于大脑中动脉区。每次卒中事件均发生在用药后3天内。3例患者入院时有高血压。虽然年龄较小，但大多数患者有多种中风风险因素。在3例脑出血患者中，我们也在脑部CT上发现了小的、低密度的病变，然而，没有临床相关性。除1例动静脉畸形外，所有血管造影均未发现血管病变或血管痉挛。与人们从之前发表的报告中推测的相反，吸入甲基苯丙胺导致脑出血的可能性至少与导致脑梗塞的可能性一样大。
Seven patients (all men, mean age 32 years, range 17-47) with stroke following methamphetamine inhalation were collected during the last 2 years. Like oral or intravenous abusers, our patients had more hemorrhagic (n = 5) than ischemic strokes (n = 2). Cases of intracerebral hemorrhage (ICH) were lobar (n = 3), caudate (n = 1) or putaminal (n = 1), whereas the infarctions were both in the middle cerebral artery region. Each stroke event occurred within 3 days after drug use. Three patients had hypertension on admission. Though young in age, most patients had multiple stroke risk factors. In 3 patients with ICH, we also found small, low attenuated lesions on the brain computed tomography, however, without clinical correlations. Except for arteriovenous malformation in 1 patient, all angiograms failed to show vasculopathy or vasospasm. Contrary to what one might surmise from previously published reports, methamphetamine inhalation is at least as likely to produce ICH as it is to produce brain infarction.