In Vivo Quantitative Reconstruction Studies of Bioluminescence Tomography: Effects of Peak-Wavelength Shift and Model Deviation
In Vivo Quantitative Reconstruction Studies of Bioluminescence Tomography: Effects of Peak-Wavelength Shift and Model Deviation
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DOI：
10.1109/tbme.2010.2056370
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发表时间：
2010-10-01
影响因子：
4.6
通讯作者：
Tian, Jie
中科院分区：
文献类型：
--
作者：
Liu, Junting;Chen, Duofang;Tian, Jie
生物发光层析成像是一种新型的光学分子成像技术。建立了相应的系统、理论和算法框架。在本研究中，我们重点分析了定量重建与发光源峰波长移的偏差和异质小鼠模型的偏差。结果表明，解剖结构动物模型的峰波长偏移和偏移对重建结果有显著影响。模型偏差对重建结果的影响远大于波长偏移。
Bioluminescence tomography is a novel optical molecular imaging technology. The corresponding system, theory, and algorithmic frames have been set up. In the present study, we concentrated on the analysis of quantitative reconstruction deviation from peak-wavelength shift of luminescent source and the deviation of heterogeneous mouse model. The findings suggest that the reconstruction results are significantly affected by the peak-wavelength shift and deviation of anatomical structure animal models. Furthermore, the model deviations exhibit much more influence than the wavelength shift on the reconstruction results.