Detection of human bocavirus in children hospitalized because of acute gastroenteritis
Detection of human bocavirus in children hospitalized because of acute gastroenteritis
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DOI：
10.1086/521366
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发表时间：
2007-10-01
影响因子：
6.4
通讯作者：
Hwang, Eung-Soo
中科院分区：
文献类型：
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作者：
Lee, Jae In;Chung, Ju-Young;Hwang, Eung-Soo
由于频繁出现胃肠道症状，有人提出人类博卡病毒（hBoV）感染可能在胃肠炎中发挥作用的观点。本研究的目的是调查患有胃肠炎的儿童中 hBoV 的患病率。我们研究了 962 名因胃肠炎住院的儿童的病因。通过酶联免疫吸附测定或逆转录酶聚合酶链反应检测病毒病原体。在 44.4% 的研究人群中发现了病毒因子：在研究人群中分别检测到轮状病毒、诺如病毒、腺病毒和星状病毒，比例分别为 25.7%、13.7%、3.0% 和 1.1%； hBoV 的检出率为 0.8%，这表明它可能在胃肠炎中发挥次要作用。
The idea that human bocavirus (hBoV) infection possibly plays a role in gastroenteritis has been suggested because of the frequent manifestation of gastrointestinal symptoms. The purpose of this study was to investigate the prevalence of hBoV in children with gastroenteritis. We studied the etiologic agents in 962 children hospitalized with gastroenteritis. Viral etiologic agents were detected by enzyme-linked immunosorbent assay or reverse-transcriptase polymerase chain reaction. A viral agent was found in 44.4% of the study population: rotavirus, norovirus, adenovirus, and astrovirus were detected in 25.7%, 13.7%, 3.0%, and 1.1% of the study population, respectively; hBoV was detected in 0.8%, which suggests that it might play a minor role in gastroenteritis.