Ugi-type Multicomponent Reaction of Nitrile Imines, Isocyanides, and Isocyanates: Effective Synthesis of 1,2,4-Triazinedione Derivatives.
Ugi-type Multicomponent Reaction of Nitrile Imines, Isocyanides, and Isocyanates: Effective Synthesis of 1,2,4-Triazinedione Derivatives.
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腈亚胺、异氰化物和异氰酸酯的 Ugi 型多组分反应：1,2,4-三嗪二酮衍生物的有效合成。
DOI：
10.1002/ajoc.201600191
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Y.
中科院分区：
文献类型：
--
作者：
Soeta;T.; Takashita;S.; Sakata;Y.; Ukaji;Y.
我们开发了一种Ugi型多组分反应，其中腈亚胺、异氰酸酯和异氰酸酯反应得到相应的1,2,4 -三嗪二酮衍生物，收率很高。这个反应是少数几个用异氰酸酯代替羧酸的基于异氰酸酯的多组分反应的例子之一。广泛的腈亚胺、异氰酸酯和异氰酸酯被发现适用于该反应。
We have developed a Ugi‐type multicomponent reaction, in which a nitrile imine, an isocyanide, and an isocyanate reacted to give the corresponding 1,2,4‐triazinedione derivatives in good‐to‐high yields. This reaction is one of the few examples of isocyanide‐based multicomponent reactions using an isocyanate in place of a carboxylic acid. A wide range of nitrile imines, isocyanides, and isocyanates were found to be applicable to the reaction.