AMIDOHYDROLASES OF BRAIN; 1 ENZYMATIC HYDROLYSIS OF N‐ACETYL‐l‐ASPARTATE AND OTHER N‐ACYL‐l‐AMINO ACIDS
AMIDOHYDROLASES OF BRAIN; 1 ENZYMATIC HYDROLYSIS OF N‐ACETYL‐l‐ASPARTATE AND OTHER N‐ACYL‐l‐AMINO ACIDS
复制标题
脑酰胺水解酶；1 N-乙酰基-L-天冬氨酸和其他 N-酰基-L-氨基酸的酶水解
DOI：
10.1111/j.1471-4159.1976.tb04434.x
复制
发表时间：
1976
影响因子：
4.7
通讯作者：
F. Goldstein
中科院分区：
文献类型：
--
作者：
F. Goldstein
–Mammalian brain contains 2 N‐acylamino acid amidohydrolases resembling the respective kidney enzymes. The anatomical and subcellular distribution of the enzymes; the substrate specificities and interspecies activities of the partially purified amidohydrolases have been studied. A considerable proportion of the amidohydrolase activity of subcellular fractions was found to be associated with the paniculate matter. The increased activities of the particulate enzymes in the presence of Triton X‐100 and chloroacetyl amino acid substrates suggest that significant amounts of the enzymes are in the bound or latent form.
