QUANTIFICATION OF THE RELATION BETWEEN ELECTROPHYSIOLOGIC AND MORPHOLOGICAL-CHANGES IN EXPERIMENTAL ENDOLYMPHATIC HYDROPS
QUANTIFICATION OF THE RELATION BETWEEN ELECTROPHYSIOLOGIC AND MORPHOLOGICAL-CHANGES IN EXPERIMENTAL ENDOLYMPHATIC HYDROPS
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DOI：
10.1177/000348949009900714
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发表时间：
1990-07-01
影响因子：
1.4
通讯作者：
SMOORENBURG, GF
中科院分区：
文献类型：
--
作者：
KLIS, SFL;BUIJS, J;SMOORENBURG, GF
对单侧内淋巴囊和导管闭塞的豚鼠耳中的水肿程度进行量化。对于来自先前研究的15只豚鼠，确定了积水程度与耳蜗功能状态的几种电生理测量之间的相关性。水肿程度与29-Hz音调引起的低频耳蜗微音的减少之间存在显著相关性，而与8-kHz探头引起的总和电位的大小之间没有相关性。水肿程度与2 kHz探头诱发的复合动作电位降低之间存在弱相关性。可能的差异的方式内淋巴管闭塞施加其影响的不同耳蜗电位进行了讨论。
The degree of hydrops in guinea pig ears that had undergone unilateral endolymphatic sac and duct obliteration was quantified. For 15 guinea pigs from a prior study, the correlation between the degree of hydrops and several electrophysiologic measures of the functional state of the cochlea was determined. A significant correlation between the degree of hydrops and a reduction in the low-frequency cochlear microphonic evoked by a 29-Hz tone was found. No correlation was found between the degree of hydrops and the magnitude of the summating potential evoked by 8-kHz probes. A weak correlation was found between the degree of hydrops and a reduction in the compound action potential evoked by 2-kHz probes. Possible differences in the way the endolymphatic duct obliteration exerts its effect on the different cochlear potentials are discussed.