HIV Incidence Among Non-Pregnant Women Living in Selected Rural, Semi-Rural and Urban Areas in Kwazulu-Natal, South Africa
HIV Incidence Among Non-Pregnant Women Living in Selected Rural, Semi-Rural and Urban Areas in Kwazulu-Natal, South Africa
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DOI：
10.1007/s10461-011-0043-7
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发表时间：
2012-10-01
影响因子：
4.4
通讯作者：
Nunn, Andrew
中科院分区：
文献类型：
--
作者：
Ramjee, Gita;Wand, Handan;Nunn, Andrew
夸祖鲁-纳塔尔省是南非艾滋病毒感染率最高的省份，特别是在年轻妇女中。为了更仔细地审查农村、半农村和城市地区未怀孕妇女的艾滋病毒流行率和发病率，对经筛选后参加三项艾滋病毒预防研究的5 753名妇女的数据进行了合并和分析。筛查时艾滋病毒感染率为43%。每季度对登记的2 523名艾滋病毒阴性妇女的艾滋病毒发病率进行测定，并根据各自的规程收集性行为和社会人口数据。在随访期间，211名妇女血清转化（6.6/100妇女年）。多变量分析发现，24岁、单身且未同居、曾发生性传播感染的千分之一货币符号妇女的血清转化率最高。夸祖鲁-纳塔尔的流行病要求在感染或传播艾滋病毒风险最高的人群中采取有针对性的艾滋病毒预防干预措施。
The province of KwaZulu-Natal has the highest prevalence of HIV in South Africa, particularly among young women. In order to more closely examine the HIV prevalence and incidence in non-pregnant women from rural, semi-rural and urban areas, data from 5,753 women screened for enrolment into three HIV prevention studies were combined and analysed. The prevalence of HIV infection was 43% at screening. HIV incidence among the 2,523 enrolled HIV-negative women was determined every quarter, and sexual behaviour and socio-demographic data were collected as per respective protocols. During follow-up, 211 women seroconverted (6.6/100 women years). Multivariate analysis found that seroconversion rates were highest among women who were a parts per thousand currency sign24 years old, single and not cohabiting, and who had incident sexually transmitted infections. The epidemic in KwaZulu-Natal calls for targeted HIV prevention interventions among those at highest risk of acquiring or transmitting infection.