Genetic factors in physical activity and the equal environment assumption - the swedish young male twins study
Genetic factors in physical activity and the equal environment assumption - the swedish young male twins study
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DOI：
10.1007/s10519-005-9018-7
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发表时间：
2006-03-01
影响因子：
2.6
通讯作者：
Tynelius, P
中科院分区：
文献类型：
--
作者：
Eriksson, M;Rasmussen, F;Tynelius, P
本研究的目的是检查遗传贡献的体力活动（PA）在全国范围内的人口的年轻成年男性双胞胎对来自瑞典和调查的平等环境假设（EEA）有关PA。于1998年和2002年通过问卷调查收集有关PA的信息，并通过结构方程模型（SEM）估计遗传因素的影响。该研究包括1022对双胞胎，最佳拟合的SEM模型给出了总PA的遗传率为49%（95% CI，40-56%），所有PA尺寸显示遗传贡献在40%和65%之间。非共享的环境因素也很重要，而共享的环境因素没有贡献的PA行为。EEA的线性回归模型进行了研究，检查是否双胞胎接触频率预测内对PA的差异，并进一步通过模拟研究。我们没有发现违反EEA的证据。
The aims of this study were to examine the genetic contribution on physical activity (PA) within a nationwide population of young adult male twin pairs from Sweden and to investigate the equal environment assumption (EEA) in relation to PA. Information on PA was collected by questionnaires in 1998 and 2002 and the impact of genetic factors was estimated by structural equation modeling (SEM). The study included 1022 pairs of twins and the best fitting SEM-model gave a heritability of 49% (95% CI, 40-56%) for total PA and all PA dimensions showed genetic contributions between 40% and 65%. Non-shared environmental factors were also important, whereas shared environmental factors did not contribute to PA behaviors. The EEA was investigated with a linear regression model, examining if the twins contact frequency predicted within-pair differences in PA, and further by a simulation study. We found no support for violation of the EEA.