Impact of untreated major depressive disorder on cognition and daily function.
Impact of untreated major depressive disorder on cognition and daily function.
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DOI：
10.4088/jcp.13086tx4c
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发表时间：
2015-07-01
期刊：
影响因子：
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通讯作者：
Culpepper, Larry
中科院分区：
文献类型：
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作者：
Culpepper, Larry
认知症状是重度抑郁症患者的一个新的临床焦点。执行功能、记忆力、注意力和处理速度的缺陷，以及负面的认知偏见，都可能导致情绪低落症状，并降低职业和社会功能。患者报告和客观测量都表明，认知症状在抑郁症患者中很常见。认知功能障碍甚至可能在第一次抑郁发作之前就存在，并且可能在情绪症状缓解后仍然存在。临床医生必须评估重度抑郁症患者的认知症状，在整个疾病过程中和缓解后监测症状，并了解这些症状如何影响日常功能。
Cognitive symptoms are an emerging clinical focus in patients with major depressive disorder. Deficits in executive function, memory, attention, and processing speed, as well as negative cognitive bias, can contribute to low mood symptoms and reduced occupational and social functioning. Both patient reports and objective measures demonstrate that cognitive symptoms are common in patients with depression. Cognitive dysfunction may be present even before the first depressive episode and may remain after mood symptoms have remitted. Clinicians must assess cognitive symptoms in their patients with major depressive disorder, monitor symptoms throughout the course of the disorder and after remission, and understand how these symptoms affect daily function.