Cytotoxicity of some medicinal plant extracts used in Tanzanian traditional medicine
Cytotoxicity of some medicinal plant extracts used in Tanzanian traditional medicine
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DOI：
10.1016/s0378-8741(99)00161-0
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发表时间：
2000-05-01
影响因子：
5.4
通讯作者：
de Witte, P
中科院分区：
文献类型：
--
作者：
Kamuhabwa, A;Nshimo, C;de Witte, P
使用民族医学数据方法，收集了坦桑尼亚传统医学中用于治疗癌症或非癌症疾病的一些坦桑尼亚植物，并对其细胞毒性活性进行了评价。在体外对三种人细胞系（HeLa，宫颈癌; HT 29，结肠腺癌;和A431，皮肤癌）评价了47种植物的甲醇提取物（10和100 μ g/ml）的抗增殖作用。在9种用于治疗癌症的植物中，2种植物（22%）表现出明显的细胞毒性作用，
Using the ethnomedical data approach, some Tanzanian plants that are used in Tanzanian traditional medicine for cancer or non-cancer diseases were collected and evaluated for cytotoxic activity. The antiproliferative effect of the methanolic extracts (10 and 100 mu g/ml) of 47 plants was evaluated in vitro on three human cell lines (HeLa, cervical carcinoma; HT29, colon adenocarcinoma; and A431, skin carcinoma). From the nine plants that are used to treat cancer, two plants (22%) exhibited pronounced cytotoxic effect (