Body mass index and mortality among US male physicians

Body mass index and mortality among US male physicians
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DOI:
10.1016/j.annepidem.2003.10.008
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发表时间:
2004-11-01
影响因子:
5.6
通讯作者:
Manson, JE
Manson, JE
中科院分区:
医学3区
文献类型:
--
作者:
Ajani, UA;Lotufo, PA;Manson, JE

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目得:为了评估在教育程度和社会经济地位均质的人群中体重指数和死亡率之间的关系,我们分析了85,078名年龄在40至84岁之间的男性的体重指数(BMI)和全因死亡率和特定原因死亡率之间的关系。在5年的随访中,我们记录了2856例死亡(包括1212例心血管疾病和891例癌症)。在年龄调整分析中,我们观察到BMI和全因死亡率之间的U型关系;在从不吸烟的男性中观察到线性关系,瘦男性的死亡率没有增加(P趋势,
PURPOSE: To assess the relationship between body mass index and mortality in a population homogeneous in educational attainment and socioeconomic status.METHODS: We analyzed the association between body mass index (BMI) and both all-cause and cause-specific mortality among 85,078 men aged 40 to 84 years from the Physicians' Health Study enrollment cohort.RESULTS: During 5 years of follow-up, we documented 2856 deaths (including 1212 due to cardiovascular diseases and 891 due to cancer). In age-adjusted analyses, we observed U-shaped relation between BMI and all-cause mortality; among men who never smoked a linear relation was observed with no increase in mortality among leaner men (P for trend,