TREATMENT OF MANIA USING A CALCIUM-ANTAGONIST - PRELIMINARY TRIAL
TREATMENT OF MANIA USING A CALCIUM-ANTAGONIST - PRELIMINARY TRIAL
复制标题
DOI：
10.1159/000118196
复制
发表时间：
1985-01-01
影响因子：
3.2
通讯作者：
CAILLARD, V
中科院分区：
文献类型：
--
作者：
CAILLARD, V
进行了一项研究，研究通过施用钙拮抗剂减少细胞质内离子钙对纯躁狂综合征的影响。 4名著名双相情感障碍患者（躁狂型）得到明显改善。 1 名患者迅速治愈，但在该病例中（一名年轻人首次发作）不能排除自发缓解的可能性。 2名患者没有任何改善，患有与脑萎缩相关的继发性躁狂状态。如果得到证实，这些结果将为未来的原发性躁狂综合征和锂对钙代谢的作用方式的研究指明方向。
A study was undertaken on the effects on pure manic syndromes of the reduction of intracytoplasmic ionized calcium by administration of a calcium antagonist. Four well-known bipolar patients (manic type) were significantly improved. 1 patient was rapidly cured, though in this case (first attack in a young man) the possibility of spontaneous remission could not be excluded. 2 patients showed no improvement, suffering from a secondary manic state related to the onset of cerebral atrophy. If confirmed, these results should orientate future research in primary manic syndromes and in the mode of action of lithium on calcium metabolism.