Quality-of-life assessment as an outcomes measure in critical limb ischemia
Quality-of-life assessment as an outcomes measure in critical limb ischemia
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DOI：
10.1016/j.jvs.2016.08.097
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发表时间：
2017-02-01
影响因子：
4.3
通讯作者：
Moneta, Gregory
中科院分区：
文献类型：
--
作者：
Alabi, Olamide;Roos, Matthew;Moneta, Gregory
严重肢体缺血（CLI）是一种存在严重合并症和高死亡率的诊断。尽管手术相关的成功如免于截肢、干预和通畅所证明，但该人群的总体生存率仍然很差。传统上，文献主要关注以医生为中心和以病变为中心的保肢手术结果，但对 CLI 患者描述以患者为中心的结果（例如生活质量 (QoL)、独立生活和步行状态）的研究仍然相对较少。对现有文献的回顾表明，尽管移植物通畅、无截肢生存率和保肢率合理，但在保肢干预后，患者的生活质量并不总是有显着提高。需要进一步研究以可测量和临床相关的方式使用生活质量工具来指导最佳质量的护理，从而最大限度地提高以患者为中心的结果。
Critical limb ischemia (CLI) is a diagnosis plagued by significant comorbidity and high mortality rates. Overall survival remains poor in this population regardless of the procedure-related success as demonstrated by freedom from amputation, intervention, and patency. The literature has traditionally focused on physician-centered and lesion-centered outcomes with regards to limb salvage procedures, but there remains a relative paucity of studies of CLI patients describing patient-centered outcomes such as quality of life (QoL), independent living, and ambulation status. Review of the available literature indicates patients do not always experience significant gains in their QoL after limb salvage interventions, despite reasonable graft patency, amputation-free survival, and limb salvage rates. Further research is required using QoL tools in a measurable and clinically relevant fashion to guide optimal quality care that maximizes patient-centered outcomes.