FATE OF INJECTED DEOXYRIBONUCLEIC ACID IN MICE
FATE OF INJECTED DEOXYRIBONUCLEIC ACID IN MICE
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DOI：
10.1038/1981088a0
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发表时间：
1963-01-01
期刊：
影响因子：
64.8
通讯作者：
IWANAGA, M
中科院分区：
文献类型：
--
作者：
TSUMITA, T;IWANAGA, M
近年来，对脱氧核糖核酸(DNA)的免疫化学研究表明，在致敏动物和系统性红斑狼疮患者血清中都存在一种特异性的抗DNA抗体。然而，动物的致敏并不总是成功的，大多数发表的关于实验动物的结果仍然有待讨论。目前需要阐明外部引入的DNA的命运。在这次通信中，氚DNA被用作示踪剂。
IN recent years, immunochemical investigations on deoxyribonucleic acid (DNA) have suggested the presence of a specific anti-DNA antibody in sensitized animals and also in patient sera of systemic lupus erythematosus. However, the sensitization of an animal has not always met success, and most of the published results about experimental animals are still open to discussion1. It is needed at present to elucidate the fate of the externally introduced DNA. In this communication, tritiated DNA was used as a tracer.