Mimicking Membrane-Related Biological Events by DNA Origami Nanotechnology

Mimicking Membrane-Related Biological Events by DNA Origami Nanotechnology
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DOI:
10.1021/acsnano.5b01723
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发表时间:
2015-04-01
期刊:
影响因子:
17.1
通讯作者:
Sugiyama, Hiroshi
Sugiyama, Hiroshi
中科院分区:
材料科学1区
文献类型:
--
作者:
Suzuki, Yuki;Endo, Masayuki;Sugiyama, Hiroshi

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One of the potential applications of DNA nanotechnology is the construction of two- or three-dimensional nanostructures that mimic the function of existing biological molecules. In this issue of ACS Nano, Kocabey et aL demonstrate that lipid-bilayer-anchored DNA origami structures can be assembled into prescribed superstructures in a programmed manner. The reported DNA-based artificial system can mimic the dynamic assembly of membrane-associated protein clusters that play an essential role in deformation of cellular membranes.