Proanthocyanidin biosynthesis - still more questions than answers?

Proanthocyanidin biosynthesis - still more questions than answers?
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DOI:
10.1016/j.phytochem.2005.01.008
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发表时间:
2005-09-01
期刊:
影响因子:
3.8
通讯作者:
Dixon, RA
Dixon, RA
中科院分区:
生物学2区
文献类型:
--
作者:
Xie, DY;Dixon, RA

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原花青素,也称为缩合单宁,是黄烷-3-醇单元的低聚物或聚合物。尽管在我们对原花色素的主要结构单元(+)-儿茶素和(-)-表儿茶素的生物合成的理解方面取得了重要突破,但关于经历聚合的分子种类的确切性质和组装机制的重要问题仍然有待回答。本文综述了近12年来有关原花青素生物合成的研究进展,并从化学、生物化学和分子遗传学的角度对原花青素合成中存在的问题进行了总结。(c)2005爱思唯尔有限公司保留所有权利。
Proanthocyanidins, also known as condensed tannins, are oligomers or polymers of flavan-3-ol units. In spite of important breakthroughs in our understanding of the biosynthesis of the major building blocks of proanthocyanidins, (+)-catechin and (-)-epicatechin, important questions still remain to be answered as to the exact nature of the molecular species that undergo polymerization, and the mechanisms of assembly. We review the structures of proanthocyanidins reported over the past 12 years in the context of biosynthesis, and summarize the outstanding questions concerning synthesis of proanthocyanidins from the chemical, biochemical and molecular genetic perspectives. (c) 2005 Elsevier Ltd. All rights reserved.