BET proteins loop and compartmentalize the 3D genome.
BET proteins loop and compartmentalize the 3D genome.
复制标题
BET 蛋白循环并划分 3D 基因组。
DOI:
10.1038/s41588-022-01031-0
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发表时间:
2022
期刊:
影响因子:
30.8
通讯作者:
Eagen,KyleP
中科院分区:
文献类型:
--
作者:
Eagen,KyleP
Chromosomes are shaped by an interplay between loop extrusion and compartmentalization. Two new studies demonstrate that bromodomain and extraterminal domain (BET) proteins contribute to both processes, with BRD4 facilitating one process and surprisingly inhibiting the other.