A Randomized Controlled Trial of the Efficacy of a Stigma Reduction Intervention for HIV-Infected Women in the Deep South

A Randomized Controlled Trial of the Efficacy of a Stigma Reduction Intervention for HIV-Infected Women in the Deep South
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DOI:
10.1089/apc.2014.0014
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发表时间:
2014-09-01
影响因子:
4.9
通讯作者:
Silva, Susan G.
Silva, Susan G.
中科院分区:
医学2区
文献类型:
--
作者:
Barroso, Julie;Relf, Michael V.;Silva, Susan G.

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本研究的目的是比较结果(自尊,应对自我效能,和内在的耻辱)在整个时间在艾滋病毒感染的妇女生活在南方腹地谁收到了耻辱减少干预(n = 51)与对照组(n = 49)谁收到了通常的护理在基线,并在30和90天。我们从诊所和艾滋病服务组织招募了99名妇女;她们被随机分配到招募地点。一个由对感染艾滋病毒的妇女进行定性元认知研究的结果制作的视频被加载到iPod Touch设备上。参与者被要求每周观看视频,持续4周,并记录他们在12周内观看视频的次数。我们检查了意向治疗组和补充完成者组疗效结局的轨迹模型结果。随着时间的推移,治疗对自尊心的改善有影响(意向治疗:p = 0.0308;完成者:p = 0.0284)和内化耻辱减少(意向治疗:p = 0.0036;完成者:p = 0.0060),以及改善应对自我效能的治疗时间效应(意向治疗:p = 0.0414;完成者:p = 0.0321)。与完成研究的对照组相比,观察到干预在提高自尊方面的中等效果。然而,干预效果的幅度很大,在减少整体耻辱,改善社会关系,减少两组的陈规定型观念。
The aim of this study was to compare outcomes (self-esteem, coping self-efficacy, and internalized stigma) across time in HIV-infected women living in the Deep South who received a stigma reduction intervention (n = 51) with those of a control group (n = 49) who received the usual care at baseline, and at 30 and 90 days. We recruited 99 women from clinics and an AIDS service organization; they were randomized by recruitment site. A video developed from the results of a qualitative metasynthesis study of women with HIV infection was loaded onto iPod Touch devices. Participants were asked to watch the video weekly for 4 weeks, and to record the number of times they viewed it over a 12-week period. We examined the trajectory model results for efficacy outcomes for the intent-to-treat and the supplemental completers groups. There was a treatment-by-time effect for improved self-esteem (intent-to-treat: p = 0.0308; completers: p = 0.0284) and decreases in internalized stigma (intent-to-treat: p = 0.0036; completers: p = 0.0060), and a treatment-by-time-by-time effect for improved coping self-efficacy (intent-to-treat: p = 0.0414; completers: p = 0.0321). A medium effect of the intervention in terms of improving self-esteem was observed when compared with the control condition in those who completed the study. The magnitude of the intervention effect, however, was large with regard to reducing overall stigma, improving social relationships, and decreasing stereotypes in both groups.