Cell surface antigens of Mycoplasma species bovine group 7 bind to and activate plasminogen.
Cell surface antigens of Mycoplasma species bovine group 7 bind to and activate plasminogen.
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DOI：
10.1128/iai.71.8.4823-4827.2003
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发表时间：
2003-08-01
影响因子：
3.1
通讯作者：
Ranson, M
中科院分区：
文献类型：
--
作者：
Bower, K;Djordjevic, SP;Ranson, M
牛支原体 7 组以赖氨酸依赖性方式在细胞表面结合纤溶酶原。细胞结合的纤溶酶原被外源尿激酶快速激活为纤溶酶，并且这种活性与纤溶酶原结合能力相关。使用用三功能交联剂修饰的纤溶酶原进行的结合测定揭示了几种结合蛋白。
Mycoplasma species bovine group 7 bound plasminogen at the cell surface in a lysine-dependent manner. Cell-bound plasminogen was rapidly activated to plasmin by exogenous urokinase, and this activity was associated with plasminogen binding capacity. Binding assays using plasminogen modified with a trifunctional cross-linking agent revealed several binding proteins.