Flow-induced wall shear stress in abdominal aortic aneurysms: Part I--steady flow hemodynamics.
Flow-induced wall shear stress in abdominal aortic aneurysms: Part I--steady flow hemodynamics.
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DOI：
10.1080/1025584021000009742
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发表时间：
2002-08-01
影响因子：
1.6
通讯作者：
Amon, Cristina H
中科院分区：
文献类型：
--
作者：
Finol, Ender A;Amon, Cristina H
在两个动脉瘤、轴对称、刚性壁模型中，采用谱元法对腹主动脉瘤（AAA）的血流模式和血流动力学应力进行了数值预测。在雷诺数10 <或=Re <或=2265的范围内，在稳定条件下模拟均匀牛顿血流。通过计算壁压（p（w））、壁切应力（tau（w））、壁切应力梯度（WSSG）的分布来量化血流动力学。血流动力学应力的最大值和雷诺数之间的相关性的建立，WSSG的空间分布被认为是一个血流动力学的力量，可能会造成损害的动脉壁在中间阶段的AAA的增长。本文第二部分讨论了脉动流中血流动力学应力的时间分布及其在AAA破裂中的物理意义。
Numerical predictions of blood flow patterns and hemodynamic stresses in Abdominal Aortic Aneurysms (AAAs) are performed in a two-aneurysm, axisymmetric, rigid wall model using the spectral element method. Homogeneous, Newtonian blood flow is simulated under steady conditions for the range of Reynolds numbers 10 < or =Re < or =2265. Flow hemodynamics are quantified by calculating the distributions of wall pressure (p(w)), wall shear stress (tau(w)), Wall Shear Stress Gradient (WSSG). A correlation between maximum values of hemodynamic stresses and Reynolds number is established, and the spatial distribution of WSSG is considered as a hemodynamic force that may cause damage to the arterial wall at an intermediate stage of AAA growth. The temporal distribution of hemodynamic stresses in pulsatile flow and their physical implications in AAA rupture are discussed in Part II of this paper.