Relationship Between Level of Blood Pressure Measured Casually and by Portable Recorders and Severity of Complications in Essential Hypertension
Relationship Between Level of Blood Pressure Measured Casually and by Portable Recorders and Severity of Complications in Essential Hypertension
复制标题
随意测量的血压和便携式记录仪测量的血压水平与原发性高血压并发症严重程度的关系
作者：
M. Sokolow;D. Werdegar;H. Kain;A. T. Hinman
研究了124例原发性高血压患者心血管并发症严重程度与动脉血压水平的关系，这些并发症根据眼底镜、心电图和X线摄影（心脏大小）标准分级。血压水平通过随意测量和在患者正常的日常活动中佩戴便携式半自动血压记录仪来确定，数据的统计分析显示高血压并发症的总体严重程度与平均随意收缩压和舒张压之间存在显著相关性;然而，与用便携式记录器获得的相应压力读数的相关性明显更高。便携式记录仪获得的平均血压与并发症严重程度之间的关系是定量的：平均收缩压和舒张压越高，平均严重程度越大，并发症严重程度与患者记录的收缩压或舒张压的变异性之间或高血压的严重程度与病程之间没有相关性。低，但显着的相关性与年龄。少数高血压并发症患者的平均记录血压水平低于120/80毫米汞柱。另一方面，所有平均记录器压力超过160/100 mm Hg的患者都有一定程度的高血压并发症。试图从患者的平均记录血压水平和年龄来预测个体病例中高血压并发症的总体严重程度，表明II级患者（中度严重程度）可与0级（无高血压并发症）研究结果支持了原发性高血压心血管并发症的严重程度主要由平均血压水平决定的观点。动脉血压建议便携式记录仪测量应有助于选择可能受益于降压治疗的患者，并指导此类治疗。
The relationship of the degree of severity of cardiovascular complications, graded according to ocular funduscopic, electrocardiographic, and roentgenographic (heart size) criteria to arterial blood pressure levels was investigated in 124 patients with essential hypertension. Blood pressure levels were determined both by casual measurements and by means of a portable semiautomatic blood pressure recorder worn during the patient's normal daily activities.Statistical analysis of the data showed a significant correlation between the overall severity of hypertensive complications and the average casual systolic and diastolic blood pressures; the correlation with the corresponding pressure readings obtained with the portable recorder, however, was significantly higher. The relationship between the average pressures obtained with the portable recorder and the severity of complications was quantitative: the higher the mean systolic and diastolic pressures, the greater the average degree of severity.No correlation was found between severity of complications and variability of the systolic or diastolic pressures recorded by the patient or between severity and duration of hypertension as best determined from the medical history. A low but significant correlation was found with age.Few patients with hypertensive complications had mean recorder blood pressure levels below 120/80 mm Hg. On the other hand, all the patients whose mean recorder pressures exceeded 160/100 mm Hg had some degree of hypertensive complications. Attempts to predict overall severity of hypertensive complications in individual cases from the patients' mean recorder blood pressure levels and age demonstrated that patients in class II (moderate severity) could be distinguished from those in class 0 (no hypertensive complications) with great accuracy.The results of the study support the view that the severity of cardiovascular complications essential hypertension is mainly determined by the average level of the arterial blood pressure. It is suggested that portable recorder measurements should aid in selecting patients likely to benefit from antihypertensive therapy and in guiding such treatment.