Plasma fibronectin in healthy newborn infants: respiratory distress syndrome and perinatal asphyxia.
Plasma fibronectin in healthy newborn infants: respiratory distress syndrome and perinatal asphyxia.
复制标题
健康新生儿的血浆纤连蛋白：呼吸窘迫综合征和围产期窒息。
DOI：
10.1016/s0022-3476(83)80257-1
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Polin,RA
中科院分区：
文献类型：
--
作者：
Yoder,MC;Douglas,SD;Gerdes,J;Kline,J;Polin,RA
材料与方法研究人群。研究组包括105名足月婴儿（56名女孩，49名男孩），体重在2250 ~ 4630 gm（平均3274 ~ + 550 gm）之间，51名早产儿（28名女孩，23名男孩），出生体重在680 ~ 2900 gm（平均2076 ~ 463 gm）之间，胎龄在28 ~ 37周（平均31 ~ + 6周）之间。所有婴儿在出生的第一天进行检查，并使用Dubowitz方法确定胎龄。5例足月婴儿和5例早产儿窒息（l-和5分钟Apgar评分< 5），15例早产儿根据公认的临床和影像学标准出现呼吸窘迫综合征。20名健康成人志愿者作为研究对照。根据费城儿童医院人体实验委员会制定的指导方针获得了家长的同意。
MATERIALS AND METHODSStudy population. The study group consisted of 105 full-term infants (56 girls, 49 boys) ranging in weight from 2250 to 4630 gm (mean 3274 _+ 550 gm) and 51 premature infants (28 girls, 23 boys) with birth weights ranging from 680 to 2900 gm (mean 2076 ___ 463 gm) and gestational ages ranging from 28 to 37 weeks (mean 31 _+ 6 weeks). All infants were examined during the first day of life and gestational ages determined using the method of Dubowitz. Five term infants and five premature infants were asphyxiated (l-and 5-minute Apgar scores< 5), and 15 premature infants had respiratory distress syndrome as defined by accepted clinical and radiographic criteria. Twenty healthy adult volunteers served as study controls. Parental consent was obtained in accordance with guidelines established by The Children's Hospital of Philadelphia Human Experimentation Committee.