Immunofluorescent detection of hormone receptors in cutaneous melanocytic tumours.
Immunofluorescent detection of hormone receptors in cutaneous melanocytic tumours.
复制标题
皮肤黑素细胞肿瘤中激素受体的免疫荧光检测。
DOI：
10.1038/bjc.1981.95
复制
发表时间：
1981-05
影响因子：
8.8
通讯作者：
Gill, P G
中科院分区：
文献类型：
--
作者：
Thompson, A J;Cook, M G;Gill, P G
在不损失诊断材料的情况下，免疫荧光评估黑素细胞肿瘤中的激素受体是非常可行的，这与定量生化分析的不切性形成对比。用这种方法，4/6的转移性黑色素瘤患者雌激素受体阳性，3/5的转移性黑色素瘤患者孕激素受体阳性。3例浅表性播散型皮肤原发黑色素瘤均未发现受体。黄体酮受体存在于一名健康人的色素痣交界处。
Immunofluorescent assessment of hormone receptors in melanocytic tumours is quite feasible without loss of diagnostic material, in contrast to the impracticability of quantitative biochemical assays. Using this method, oestrogen receptors were demonstrated in 4/6, and progesterone receptors in 3/5 patients with metastatic melanoma. Receptors were not found in 3 patients with primary cutaneous melanomas of the superficial spreading type. Progesterone receptors were present in the junctional component of a naevus from one healthy person.