Muscle mass and intramuscular fat of the quadriceps are related to muscle strength in non-ambulatory chronic stroke survivors: A cross-sectional study.
Muscle mass and intramuscular fat of the quadriceps are related to muscle strength in non-ambulatory chronic stroke survivors: A cross-sectional study.
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DOI：
10.1371/journal.pone.0201789
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发表时间：
2018
期刊：
影响因子：
3.7
通讯作者：
Moriyama H
中科院分区：
文献类型：
--
作者：
Akazawa N;Harada K;Okawa N;Tamura K;Moriyama H
改善大腿中部的肌肉质量和肌内脂肪可以增加慢性卒中存活者瘫痪和非瘫痪肢体的肌肉力量。与能走动的幸存者相比，不能走动的患者的两条肢体的股四头肌的肌肉质量和肌肉力量显著降低，肌内脂肪增加。因此，考虑到瘫痪下肢功能在慢性期不能充分恢复，改善肌肉质量和肌内脂肪可能有助于提高卧床慢性卒中幸存者的四头肌肌力。然而，这些关系仍然不清楚。本研究的目的是阐明不能行走的慢性卒中幸存者的四头肌的肌力、肌肉质量和肌内脂肪之间的关系。研究设计：横断面研究。参与者：50名卧床慢性卒中幸存者。主要观察指标：使用手持式测力计测量股四头肌肌力。使用B型超声成像采集横向超声图像。分别根据肌肉厚度和回声强度评估股四头肌的肌肉质量和肌内脂肪。数据分析：逐步多元回归分析被用来确定与轻瘫和非轻瘫肢体的股四头肌肌力独立相关的因素。为了避免多重共线性，将肌肉厚度和回声强度输入单独的多元回归模型。以轻瘫或非轻瘫肢体的肌肉厚度或回声强度以及其他混杂因素为自变量。肌肉厚度呈正相关，回声强度呈负相关的轻瘫和非轻瘫肢体的股四头肌肌力。四头肌的肌肉质量和肌内脂肪与不能行走的慢性卒中幸存者的肌肉力量有关。增加四肢四头肌的肌肉质量和减少肌内脂肪可以提高肌肉力量。
Improving muscle mass and intramuscular fat in the mid-thigh increases the muscle strength of the paretic and non-paretic limbs in ambulatory chronic stroke survivors. There is a remarkable decrease in muscle mass and muscle strength and an increase in intramuscular fat in the quadriceps of both limbs of non-ambulatory compared with ambulatory survivors. Therefore, given that paretic lower extremity function does not recover sufficiently in the chronic phase, it may be helpful to improve muscle mass and intramuscular fat to increase muscle strength in the quadriceps of non-ambulatory chronic stroke survivors. However, these relationships remain unclear. The purpose of this study was to clarify the relationships between muscle strength, muscle mass, and intramuscular fat of the quadriceps in non-ambulatory chronic stroke survivors. Study design: A cross-sectional study. Participants: Fifty non-ambulatory chronic stroke survivors. Main outcome measures: Quadriceps muscle strength was measured using a handheld dynamometer. Transverse ultrasound images were acquired using B-mode ultrasound imaging. Muscle mass and intramuscular fat of the quadriceps were assessed based on muscle thickness and echo intensity, respectively. Data analysis: Stepwise multiple regression analyses were used to identify the factors independently associated with the quadriceps muscle strength of the paretic and non-paretic limbs. To avoid multicollinearity, muscle thickness and echo intensity were entered into separate multiple regression models. Muscle thickness or echo intensity of the paretic or non-paretic limbs and other confounding factors were set as the independent variables. Muscle thickness was positively related and echo intensity was negatively related to the quadriceps muscle strength of the paretic and non-paretic limbs. Muscle mass and intramuscular fat of the quadriceps are related to muscle strength in non-ambulatory chronic stroke survivors. Increasing muscle mass and decreasing intramuscular fat of the quadriceps of both limbs may improve muscle strength.
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DOI：
10.1016/s0003-9993(95)80038-7
发表时间：
1995-01-01
影响因子：
4.3
作者：
JORGENSEN, HS;NAKAYAMA, H;OLSEN, TS
通讯作者：
OLSEN, TS
影响因子：
4.2
作者：
Chen, I-Hsuan;Yang, Yea-Ru;Wang, Ray-Yau
通讯作者：
Wang, Ray-Yau
影响因子：
3.7
作者：
Parry, Selina M.;El-Ansary, Doa;Denehy, Linda
通讯作者：
Denehy, Linda
影响因子：
3.2
作者：
Prado-Medeiros, Christiane L.;Silva, Milla P.;Salvini, Tania F.
通讯作者：
Salvini, Tania F.
影响因子：
3
作者：
Miyatani, M;Kanehisa, H;Fukunaga, T
通讯作者：
Fukunaga, T