Eosinophils and resistance to Trichinella spiralis.
Eosinophils and resistance to Trichinella spiralis.
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DOI：
10.1084/jem.145.3.755
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发表时间：
1977-03-01
影响因子：
15.3
通讯作者：
Warren, K S
中科院分区：
文献类型：
--
作者：
Grove, D I;Mahmoud, A A;Warren, K S
通过反复给予兔抗小鼠嗜酸性粒细胞血清，使感染旋毛虫的小鼠嗜酸性粒细胞耗竭。对蠕虫从小肠中自发排出没有影响，但肌肉中的幼虫数量几乎增加了一倍。它的结论是嗜酸性粒细胞有助于抵抗旋毛虫病的全身阶段。
Mice infected with Trichinella spiralis were depleted of eosinophils by repeated administration of rabbit anti-mouse eosinophil serum. There was no effect on the spontaneous expulsion of adult worms from the small intestines, but the numbers of larvae in the muscles were almost doubled. It is concluded that eosinophils contribute to resistance to the systemic phase of trichinosis.