Genetically dissociated components of working memory: evidence from Down's and Williams syndrome
Genetically dissociated components of working memory: evidence from Down's and Williams syndrome
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DOI：
10.1016/s0028-3932(98)00128-6
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发表时间：
1999-06-01
期刊：
影响因子：
2.6
通讯作者：
Hewes, AK
中科院分区：
文献类型：
--
作者：
Jarrold, C;Baddeley, AD;Hewes, AK
王晓明，王晓明，王晓明，等[J]；[16:37 . 22]表明唐氏和威廉姆斯综合症可能与特定的和对比性的工作记忆缺陷有关；唐氏综合症的语言短期记忆受损，威廉姆斯综合症的视觉空间短期记忆缺陷。在两项研究中，我们研究了这些明显的缺陷是否仅仅是与这些障碍相关的学习困难的一般模式的结果。实验1用协方差分析来控制心理年龄差异，比较了这些组的语言和视觉空间短期记忆能力。实验2将Williams综合征患者与非言语心理年龄进行配对，比较配对组的短期记忆能力。这两个实验的结果与Wang和Bellugi报道的结果大致一致，并支持工作记忆可以被分离成单独的子系统的观点。1999爱思唯尔科学有限公司版权所有。
Wang and Bellugi [J clin exp Neuropsychol 1994;16:317-22] have suggested that Down's and Williams syndrome might be associated with specific and contrasting working memory deficits; with impaired verbal short-term memory in Down's syndrome, and a visuo-spatial short-term memory deficit in Williams syndrome. In two studies we examine whether these apparent deficits might simply be a consequence of the general pattern of learning difficulties associated with these disorders. Experiment 1 compared verbal and visuo-spatial short-term memory abilities in these groups, using analysis of covariance to control for mental age differences. In Experiment 2 individuals with Williams syndrome were matched to control groups for non-verbal mental age, and the short-term memory abilities of these matched groups were compared. The results of both experiments are broadly consistent with those reported by Wang and Bellugi, and support the view that working memory can be dissociated into Separate subsystems. (C) 1999 Elsevier Science Ltd. All rights reserved.