Prevalence of symptoms of vaginal fistula in 19 sub-Saharan Africa countries: a meta-analysis of national household survey data
Prevalence of symptoms of vaginal fistula in 19 sub-Saharan Africa countries: a meta-analysis of national household survey data
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DOI：
10.1016/s2214-109x(14)70348-1
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发表时间：
2015-05-01
影响因子：
34.3
通讯作者：
Kirakoya-Samadoulougou, Fati
中科院分区：
文献类型：
--
作者：
Maheu-Giroux, Mathieu;Filippi, Veronique;Kirakoya-Samadoulougou, Fati
背景 阴道瘘是一种严重的医学疾病，其特征是阴道与膀胱或直肠之间的异常开口，导致尿液或粪便持续漏出。这种疾病在撒哈拉以南非洲造成的负担尚不确定。我们使用基于症状自我报告的全国家庭调查来估计该地区阴道瘘症状的终生流行率和点流行率。方法我们考虑了撒哈拉以南非洲地区的所有人口统计和健康调查 (DHS) 和多指标整群调查 (MICS)，并纳入了育龄妇女（15-49 岁）的数据。我们利用贝叶斯分层荟萃分析估计了阴道瘘的终生患病率和点患病率。结果 我们在分析中纳入了 19 项调查，包括 262 100 名受访者。终生患病率为3 .每1000名育龄妇女中有0例（95%可信区间1.3-5.5）。估算缺失数据后，点患病率为每 1000 名育龄妇女 1.0 例 (0.3-2.4)。埃塞俄比亚目前有阴道瘘症状的妇女人数最多。 解释 这项研究首次利用国家代表性调查数据来估计 19 个撒哈拉以南非洲国家的阴道瘘负担。点流行率略低于先前估计的值，但这些早期估计值处于流行率的可信区间内。尽管阴道瘘相对罕见，但在撒哈拉以南非洲地区仍然很常见。
Background Vaginal fistula is a serious medical disorder characterised by an abnormal opening between the vagina and the bladder or rectum, which results in continuous leakage of urine or stool. The burden of this disorder in sub-Saharan Africa is uncertain. We estimated the lifetime and point prevalence of symptoms of vaginal fistula in this region using national household surveys based on self-report of symptoms.Methods We considered all Demographic and Health Surveys (DHS) and Multiple Indicators Cluster Surveys (MICS) from sub-Saharan Africa and included data for women of reproductive age (15-49 years). We estimated lifetime prevalence and point prevalence of vaginal fistula with use of Bayesian hierarchical meta-analysis.Findings We included 19 surveys in our analysis, including 262 100 respondents. Lifetime prevalence was 3 . 0 cases (95% credible interval 1.3-5.5) per 1000 women of reproductive age. After imputation of missing data, point prevalence was 1.0 case (0.3-2.4) per 1000 women of reproductive age. Ethiopia had the largest number of women who presently have symptoms of vaginal fistula.Interpretation This study is the first to estimate the burden of vaginal fistula in 19 sub-Saharan Africa countries using nationally representative survey data. Point prevalence was slightly lower than previously estimated but these earlier estimates are within the prevalence's credible intervals. Although vaginal fistula is relatively rare, it is still too common in sub-Saharan Africa.