Murine natural killer cell activation receptors
Murine natural killer cell activation receptors
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小鼠自然杀伤细胞激活受体
作者：
H. Smith;Azza H. Idris;W. Yokoyama
自然杀伤细胞（NK）表达两种参与目标识别的受体：针对目标细胞MHC I类分子的抑制受体和激活受体。虽然对抑制受体的理解已经取得了重大进展，但对激活受体的了解却很少。对几种小鼠NK细胞激活受体的详细分析提供了这些受体在先天免疫反应中的生理相关性。
Summary: Natural killer (NK) cells express two types of receptors involved in target recognition: inhibitory receptors for target cell MHC class I molecules and activation receptors. While there has been significant progress in understanding the inhibitory receptors, less is known about the activation receptors. Detailed analysis of several mouse NK‐cell activation receptors provides insight into the physiologic relevance of these receptors in the innate immune response.