The Potential of Biosurfactants in the Pharmaceutical Industry: A Review

The Potential of Biosurfactants in the Pharmaceutical Industry: A Review
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生物表面活性剂在制药行业的潜力:综述

DOI:
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发表时间:
2022
期刊:
Bioequivalence & Bioavailability International Journal
影响因子:
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通讯作者:
S. V
S. V
中科院分区:
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文献类型:
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作者:
S. V

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被称为“生物基表面活性剂”的表面活性物质来自多种来源,包括植物、动物、微生物、海洋生物、合成物和半合成物。生物基表面活性剂具有多种用途,包括食品、个人护理、制药和工业配方以及农业和油田化学品以及机构和工业清洁。如今,由于全球各国政府对洗涤剂中毒素的使用制定了严格的环境规则以及消费者日益关注的环境问题,市场上对生物基表面活性剂的需求量很大。由于其低毒性和可生物降解性,生物基表面活性剂被认为是传统石化基表面活性剂的更环保的替代品。因此,正在进行更多研究,通过生物过程或利用可再生资源(包括生物催化或发酵)来创造创新的可生物降解表面活性剂。本文讨论了许多此类品种、它们的特性、表面活性剂配方的临床评估、生物基表面活性剂的使用、工业最新技术以及生物基表面活性剂制造的前景市场。
Surface-active substances known as "bio-based surfactants" come from a variety of sources, including plants, animals, microorganisms, marine life, synthetics, and semi-synthetics. Bio-based surfactants have a variety of uses, including in food, personal care, pharmaceutical, and industrial formulations as well as in agricultural and oil field chemicals and institutional and industrial cleaning. Nowadays, there is a significant demand for bio-based surfactants on the market as a result of the strict environmental rules that governments across the globe have placed on the use of toxins in detergents and growing environmental concerns among consumers. Due to their low toxicity and biodegradability, bio-based surfactants are acknowledged as a more environmentally friendly alternative to traditional petrochemical-based surfactants. Additional research going on for the creation of innovative biodegradable surfactants as a result, either by biological processes or from renewable resources (bio-catalysis or fermentation are included). Many such varieties, their properties, clinical assessment of surfactant formulations, use of bio-based surfactants, industrial state-of-the-art, and prospective markets for bio-based surfactants manufacturing are discussed in this paper.