Atrial fibrillation-induced atrial contractile dysfunction: a tachycardiomyopathy of a different sort

Atrial fibrillation-induced atrial contractile dysfunction: a tachycardiomyopathy of a different sort
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DOI:
10.1016/s0008-6363(01)00453-9
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发表时间:
2002-01-01
影响因子:
10.8
通讯作者:
Allessie, M
Allessie, M
中科院分区:
医学1区
文献类型:
--
作者:
Schotten, U;Greiser, M;Allessie, M

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目的:虽然 AF 诱发的心房收缩功能障碍具有重要的临床意义,但对潜在的细胞内机制知之甚少,方法:从 59 名连续接受二尖瓣手术的患者(31 名 SR 患者,28 名慢性 AF 患者)的右心耳中提取薄肌制剂(diaineter)
Objective: Although AF-induced atrial contractile dysfunction has significant clinical implications the underlying intracellular mechanisms are poorly understood, Methods: From the right atrial appendages of 59 consecutive patients undergoing mitral valve surgery (31 in SR, 28 in chronic AF) thin muscle preparations (diaineter