Modulation of radial blood flow during Braille character discrimination task
Modulation of radial blood flow during Braille character discrimination task
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DOI：
10.1556/aphysiol.99.2012.1.3
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发表时间：
2012-03-01
影响因子：
--
通讯作者：
Tsuchimochi, H.
中科院分区：
文献类型：
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作者：
Murata, J.;Matsukawa, K.;Tsuchimochi, H.
目的：人类的手在执行感觉和运动功能方面表现出色。我们假设在集中的手指感知过程中，手部的血流受交感神经输出动态调节。为了验证这一假设，我们在9名健康受试者在盲态下进行盲文阅读时，测量了桡动脉血流（RBF）、桡动脉血管传导性（RVC）、心率（HR）和动脉血压（AP）。受试者被要求用食指阅读一块带有凸起字母的平板（盲文阅读）30秒，并触摸一块空白平板作为盲文识别过程的对照。
结果：在盲文阅读过程中，心率和动脉血压略有升高，但在触摸空白平板时保持不变。在盲文字符识别任务中，桡动脉血流和桡动脉血管传导性降低（分别降低了 -46%和 -49%）。此外，在盲文字符识别任务中，桡动脉血流和桡动脉血管传导性的变化比触摸空白平板时大得多（分别降低了 -20%和 -20%）。
结论：这些结果表明，在集中的手指感知过程中，手部的血流分布通过交感神经活动进行调节。
Purpose: Human hands are excellent in performing sensory and motor function. We have hypothesized that blood flow of the hand is dynamically regulated by sympathetic outflow during concentrated finger perception. To identify this hypothesis, we measured radial blood flow (RBF), radial vascular conductance (RVC), heart rate (HR), and arterial blood pressure (AP) during Braille reading performed under the blind condition in nine healthy subjects. The subjects were instructed to read a flat plate with raised letters (Braille reading) for 30 s by the forefinger, and to touch a blank plate as control for the Braille discrimination procedure. Results: HR and AP slightly increased during Braille reading but remained unchanged during the touching of the blank plate. RBF and RVC were reduced during the Braille character discrimination task (decreased by -46% and -49%, respectively). Furthermore, the changes in RBF and RVC were much greater during the Braille character discrimination task than during the touching of the blank plate (decreased by -20% and -20%, respectively). Conclusions: These results have suggested that the distribution of blood flow to the hand is modulated via sympathetic nerve activity during concentrated finger perception.