A comparison of dermal and cadaveric pericardial, grafts in the modified Horton-Devine procedure for Peyronie's disease
A comparison of dermal and cadaveric pericardial, grafts in the modified Horton-Devine procedure for Peyronie's disease
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DOI：
10.1016/s0022-5347(05)66106-x
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发表时间：
2001-07-01
影响因子：
6.6
通讯作者：
Carson, CC
中科院分区：
文献类型：
--
作者：
Chun, JL;McGregor, A;Carson, CC
目的：阴茎硬结病引起的阴茎弯曲常采用斑块切开或切除移植治疗。各种移植材料的优点长期以来一直存在争议。我们研究的结果，真皮和尸体心包移植斑块切开或切除后的Peyronie's diseases.Materials和方法：我们回顾性评估所有修改霍顿迪瓦恩程序之间进行1998年2月和2000年4月。采用下腹部真皮或市售尸体心包覆盖皮质缺损。一个后续的电话问卷调查，以确定病人的满意度和functions.Results：我们回顾了27名男子，包括18和9谁收到了真皮和心包移植，分别记录。我们成功联系了24例患者，包括15例真皮移植和9例心包移植，以评估满意度。术后平均随访10个月。在24例患者中，22例报告性交成功，15例（63%）需要帮助以获得足够的勃起刚性以获得满意的性交。8名患者报告复发性弯曲，这是最小的，并没有妨碍性功能。总的来说，11的15例皮肤和8的9个心包移植将再次接受手术或推荐给others.Conclusions：真皮和尸体心包移植的结果是可比的。最小的术前准备，降低病人的发病率和尸体心包的柔韧性，使其成为一个有吸引力的合适的移植物替代改良Horton-Devine程序。需要更长时间的随访和更大的患者系列来证实尸体心包的优势。
Purpose: Penile curvature due to Peyronie's disease is often treated with plaque incision or excision and grafting. The advantages of various graft materials have long been debated. We studied the outcomes of dermal and cadaveric pericardial grafts after plaque incision or excision for Peyronie's disease.Materials and Methods: We retrospectively evaluated all modified Horton-Devine procedures performed between February 1998 and April 2000. Dermal graft harvested from the lower abdomen or commercially available cadaveric pericardium was used to cover the corporeal defect. A followup telephone questionnaire was administered to determine patient satisfaction and function.Results: We reviewed the records of 27 men, including 18 and 9 who received a dermal and pericardial graft, respectively. We successfully contacted 24 patients, including 15 with a dermal and 9 with a pericardial graft, to evaluate satisfaction. Average postoperative followup was 10 months. Of the 24 patients, 22 reported successful coitus and 15 (63%) needed assistance to achieve erection rigid enough for satisfactory coitus. Eight patients reported recurrent curvature, which was minimal and did not hamper sexual function. Overall 11 of the 15 patients with a dermal and 8 of the 9 with a pericardial graft would undergo the surgery again or recommend it to others.Conclusions: The results of the dermal and cadaveric pericardial grafts were comparable. The minimal preoperative preparation, decreased patient morbidity and pliability of cadaveric pericardium make it an attractive suitable graft substitute in the modified Horton-Devine procedure. Longer followup and larger patient series are needed to confirm the advantages of cadaveric pericardium.