Oral Complications of Cancer and Cancer Therapy From Cancer Treatment to Survivorship
Oral Complications of Cancer and Cancer Therapy From Cancer Treatment to Survivorship
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DOI：
10.3322/caac.21157
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发表时间：
2012-11-01
影响因子：
254.7
通讯作者：
Maghami, Ellie
中科院分区：
文献类型：
--
作者：
Epstein, Joel B.;Thariat, Juliette;Maghami, Ellie
由癌症和癌症治疗引起的口腔并发症会导致急性和晚期毒性，这些毒性可能被低估、认识不足和治疗不足。癌症治疗的最新进展导致口腔并发症的发病率、性质和严重程度发生变化。随着幸存者数量的增加，人们越来越认识到，需要积极管理口腔毒性，以确保最佳的长期口腔健康和整体福祉。护理的进步对以前认识到的口腔并发症产生了影响，并导致新认识到的不良反应。在这里，作者简要回顾了癌症治疗的进展，包括手术、口腔护理、放射治疗、造血细胞移植和肿瘤内科学的最新进展;描述了这些进展如何影响口腔健康;并讨论了与癌症相关的常见和/或严重的口腔健康并发症和癌症治疗及其对长期健康的影响。虽然癌症治疗的一些急性口服毒性可能会减少，但它们基本上仍然不可避免。长期并发症的重大影响需要提高认识和认识，以促进预防和适当干预。因此，重要的是初级肿瘤学家要意识到这些并发症，以便及时采取适当的措施。预防和管理最好通过多学科保健小组提供，这些小组必须整合和有效沟通，以便在适当的时候以协调的方式提供最佳的病人护理。CA Cancer J Clin 2012;62：400-422. (C)2012年美国癌症协会
Oral complications resulting from cancer and cancer therapies cause acute and late toxicities that may be underreported, underrecognized, and undertreated. Recent advances in cancer treatment have led to changes in the incidence, nature, and severity of oral complications. As the number of survivors increases, it is becoming increasingly recognized that the aggressive management of oral toxicities is needed to ensure optimal long-term oral health and general well-being. Advances in care have had an impact on previously recognized oral complications and are leading to newly recognized adverse effects. Here, the authors briefly review advances in cancer therapy, including recent advances in surgery, oral care, radiation therapy, hematopoietic cell transplantation, and medical oncology; describe how these advances affect oral health; and discuss the frequent and/or severe oral health complications associated with cancer and cancer treatment and their effect upon long-term health. Although some of the acute oral toxicities of cancer therapies may be reduced, they remain essentially unavoidable. The significant impact of long-term complications requires increased awareness and recognition to promote prevention and appropriate intervention. It is therefore important for the primary oncologist to be aware of these complications so that appropriate measures can be implemented in a timely manner. Prevention and management is best provided via multidisciplinary health care teams, which must be integrated and communicate effectively in order to provide the best patient care in a coordinated manner at the appropriate time. CA Cancer J Clin 2012;62:400-422. (C) 2012 American Cancer Society.