A direct comparison of immunological characteristics of granulocyte colony-stimulating factor (G-CSF)-primed bone marrow grafts and G-CSF-mobilized peripheral blood grafts.
A direct comparison of immunological characteristics of granulocyte colony-stimulating factor (G-CSF)-primed bone marrow grafts and G-CSF-mobilized peripheral blood grafts.
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发表时间：
2005
期刊：
影响因子：
10.1
通讯作者：
Huang Xiao Jun;Chang Ying Jun;Z. Yu
中科院分区：
文献类型：
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作者：
Huang Xiao Jun;Chang Ying Jun;Z. Yu
我们的初步结果表明，粒细胞集落刺激因子(G-CSF)诱导的骨髓(G-BM)和G-CSF动员的外周血移植(G-PB)在免疫细胞和1型和2型细胞因子方面存在着数量和质量上的差异。我们的发现表明，在G-BM中，T细胞低反应性较低，T细胞从Th1到Th2的极化更容易。
Our preliminary results suggest the existence of quantitative and qualitative differences in immune cells and type1 and type2 cytokines between granulocyte colony-stimulating factor (G-CSF) primed bone marrow (G-BM) and G-CSF-mobilized peripheral blood grafts (G-PB). Our findings suggest that lower T-cell hyporesponsiveness and easier polarization of T cells from Th1 to Th2 are found in G-BM.