Evaluation of cardiac cone-beam single photon emission computed tomography using observer performance experiments and receiver operating characteristic analysis.
Evaluation of cardiac cone-beam single photon emission computed tomography using observer performance experiments and receiver operating characteristic analysis.
复制标题
使用观察者性能实验和接收器操作特性分析评估心脏锥束单光子发射计算机断层扫描。
DOI：
10.1097/00004424-199312000-00004
复制
发表时间：
1993
影响因子：
6.7
通讯作者：
Gullberg,GT
中科院分区：
文献类型：
--
作者：
Tsui,BM;Terry,JA;Gullberg,GT
理由和目标。使用锥束准直器的单光子发射计算机断层扫描 (SPECT) 改善了心脏成像的检测效率和空间分辨率之间的权衡。然而，使用焦点保持在平面上的轨道进行采集并不能为精确重建提供足够的数据。在当前的研究中，作者评估了平面轨道锥束 SPECT 在检测简单心肌缺陷中的临床效用。观察者性能实验使用计算机模拟心脏模型，对心肌缺损检测中的高分辨率锥束与相同分辨率平行孔和扇形束准直器设计进行了比较。心肌和其他组织器官对铊 201 的吸收通过数学三维上躯干模型进行建模，并从中模拟物理上真实的投影。八名观察者观看了三种准直器设计的重建横轴图像，并表明了他们在指定位置检测到高斯形缺陷的确定性。 结果。接收器工作特性曲线下的面积表明，无论切片位置如何，锥束设计都优于扇形束，而对于指定的检测任务，扇形束设计又优于平行孔设计。结论。观察者研究表明，与使用平行孔和扇形束准直器的传统心脏 SPECT 相比，数据采样不足导致的重建伪影不会限制从平面轨道锥束心脏 SPECT 图像获得改进的诊断信息。
RATIONALE AND OBJECTIVES. Single photon emission computed tomography (SPECT) with a cone–beam collimator improves the trade-off between detection efficiency and spatial resolution for cardiac imaging. However, acquisitions using orbits where the focus remains in a plane do not provide sufficient data for exact reconstruction. In the current study the authors evaluate the clinical utility of planar-orbit cone–beam SPECT in detecting a simple myocardial defect.METHODS. Observer performance experiments compared high-resolution cone–beam with same-resolution parallel-hole and fan–beam collimator designs in myocardial defect detection using a computer-simulated cardiac model. The uptake of Thallium-201 in the myocardium and other tissue organs was modeled by a mathematical three-dimensional upper torso phantom from which physically realistic projections were simulated. Eight observers viewed reconstructed transaxial images from the three collimator designs and indicated the certainty with which they detected a Gaussian-shaped defect at a specified location.RESULTS. The area under the receiver operating characteristic curve indicated that the cone–beam design, regardless of slice position, was superior to the fan–beam, which in turn was superior to the parallel-hole design for the specified detection task.CONCLUSIONS. The observer study demonstrated that reconstruction artifacts resulting from insufficient data sampling do not binder obtaining improved diagnostic information from planar-orbit cone–beam cardiac SPECT images compared to conventional cardiac SPECT using parallel-hole and fan–beam collimators.