Porphyrins conjugated to DNA as CD reporters of the salt-induced B to Z-DNA transition
Porphyrins conjugated to DNA as CD reporters of the salt-induced B to Z-DNA transition
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DOI：
10.1039/b603409h
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发表时间：
2006-01-01
影响因子：
3.2
通讯作者：
Berova, N
中科院分区：
文献类型：
--
作者：
Balaz, M;Li, BC;Berova, N
结合在寡核苷酸5'位置的卟啉发色团允许在微摩尔浓度下，通过420 nm左右的卟啉Soret带圆二色激子偶联信号和300 nm以下的寡核苷酸CD区同时检测B-到Z-DNA的过渡。
The porphyrin chromophore incorporated at the 5'-position of an oligonucleotide allows the simultaneous detection of the B- to Z-DNA transition via the porphyrin Soret band circular dichroism exciton couplet signal around 420 nm and the oligonucleotide CD region below 300 nm, at micromolar concentrations.