Evanescent field-based optical fiber sensing device for measuring the refractive index of liquids in microfluidic channels
Evanescent field-based optical fiber sensing device for measuring the refractive index of liquids in microfluidic channels
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DOI：
10.1364/ol.30.001273
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发表时间：
2005-06-01
期刊：
影响因子：
3.6
通讯作者：
Mansuripur, M
中科院分区：
文献类型：
--
作者：
Polynkin, P;Polynkin, A;Mansuripur, M
我们报道了一种简单的光学传感装置，能够测量在微流体通道中传播的液体的折射率。该传感器是基于一个单模光纤，是锥形的亚微米尺寸和沉浸在透明的可固化软聚合物。用于液体分析物的通道在紧邻锥形腰部处产生。通过光纤的锥形部分传播的光延伸到通道中，使得系统中的光损耗对聚合物和液体之间的折射率差敏感。描述了原型传感器件的制造过程和测试。该传感器既可作为高响应开关器件运行，也可在连续测量模式下运行，其折射率测量的估计精度接近5 X 10（-4）。(c)2005年美国光学学会
We report a simple optical sensing device capable of measuring the refractive index of liquids propagating in microfluidic channels. The sensor is based on a single-mode optical fiber that is tapered to submicrometer dimensions and immersed in a transparent curable soft polymer. A channel for liquid analyte is created in the immediate vicinity of the taper waist. Light propagating through the tapered section of the fiber extends into the channel, making the optical loss in the system sensitive to the refractive-index difference between the polymer and the liquid. The fabrication process and testing of the prototype sensing devices are described. The sensor can operate both as a highly responsive on-off device and in the continuous measurement mode, with an estimated accuracy of refractive-index measurement of similar to 5 X 10(-4). (c) 2005 Optical Society of America