Cellular transformation by human papillomavirus DNA in vitro.
Cellular transformation by human papillomavirus DNA in vitro.
复制标题
人乳头瘤病毒 DNA 体外细胞转化。
DOI:
10.1126/science.6330900
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发表时间:
1984
期刊:
影响因子:
--
通讯作者:
Faras,AJ
中科院分区:
文献类型:
--
作者:
Watts,SL;Phelps,WC;Ostrow,RS;Zachow,KR;Faras,AJ
Molecularly cloned DNA's of human papillomaviruses HPV-5 and HPV-1 induced morphological transformation of mouse C127 cells in culture. Single-cell clones of cells transformed by papillomavirus contained multiple persistent episomal copies of the transfected DNA species and were analyzed for growth characteristics indicating malignant potential.