The Histology of the Skin Lesions in Varicella.
The Histology of the Skin Lesions in Varicella.
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水痘皮肤病变的组织学。
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E. E. Tyzzer
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作者：
E. E. Tyzzer
虽然水痘通常被认为是一种儿童疾病，但以下报告完全涉及成人皮肤病变。这些病例是在菲律宾马尼拉比利比德监狱的菲律宾成年男性囚犯中观察到的。关于这种疾病在岛屿上的流行情况，我只能获得很少的信息。在一些地方，它被当地人认为是一种独特的疾病，在他加禄语中被称为“buuton tubig”或水痘，以区别于“buuton”或天花。在其中一个省，人们遇到了一个因以前患过天花而脸上有凹陷的土著男孩，他表现出水痘的典型症状。成人偶尔发生水痘是被普遍接受的，尽管一些著名的权威声称从未见过一例。托马斯16说，他从未见过成人感染水痘的病例，而成人身上类似水痘的疹表明患有水痘。冯·根瑟（Von Genser）分析了29,250例水痘病例，发现98.22%发生在15岁之前，1.78%发生在15岁至61岁之间。种族、气候和拥挤监狱的监禁无疑是使成年人更容易患这种疾病的原因。在本文所处理的病例中，诊断是通过接种实验、皮肤病变的组织学以及疾病的临床特征来确定的。天花和水痘在病原学上是否相同，但又不同，以前是一个有争议的问题
Although varicella is generally regarded as a disease of childhood, the following report deals entirely with the skin lesions in adults. These cases were observed among adult male Filipinos, inmates of Bilibid Prison, at Manila, P.l. Concerning the prevalence of this disease in the islands I could obtain but scanty information. In some localities it is recognized by the natives as a distinct disease, and is called in the Tagalog " buluton tubig" or waterpox, to distinguish it from " buluton " or smallpox. In one of the provinces a native boy, with face pitted from a former attack of smallpox, was met with who showed the characteristic eruption of varicella. The occasional occurrence of varicella in adults is generally accepted, althoughl some eminent authorities clairn never to have seen a case. Thomas 5 16 states that he never saw a case in an adult, and that eruptions resembling varicella in adults indicate variola. Von Genser c has analyzed 29,250 cases of varicella, and finds that 98.22 per cent occurred before the fifteenth year of life, and I.78 per cent between the fifteenth and sixty-first year. Race, climnate, and confinement in crowded prisons doubtless contribute to nmake adults more susceptible to this disease. In the cases dealt with in this paper the diagnosis was definitely established by inoculation experiments, and by the histology of the skin lesions as well as by the clinical features of the disease. It was formerly a matter of controversy whether variola and varicella are etiologically identical, and but different