Co-activation differences in lower limb muscles between asymptomatic controls and those with varying degrees of knee osteoarthritis during walking
Co-activation differences in lower limb muscles between asymptomatic controls and those with varying degrees of knee osteoarthritis during walking
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DOI：
10.1016/j.clinbiomech.2009.02.005
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发表时间：
2009-06-01
影响因子：
1.8
通讯作者：
Stanish, William D.
中科院分区：
文献类型：
--
作者：
Hubley-Kozey, Cheryl L.;Hill, Nicholas A.;Stanish, William D.
背景资料：步态期间肌肉共激活增加已被确定为与膝关节骨关节炎相关的神经肌肉改变，但尚未确定不同骨关节炎严重程度之间的共激活水平。本研究的目的是使用共激活指数和模式识别技术来确定是否可以在无症状对照组、中度和重度骨关节炎患者中检测到共激活的差异。记录了63例无症状患者的股外侧肌和内侧肌、外侧和内侧腘绳肌和腓肠肌对的表面肌电图，59名中度和48名重度骨关节炎受试者在自选步行过程中。共激活指数计算超过初始的立场为四个内侧和外侧肌肉对。使用单因素ANOVA（α = 0.05）在各组之间检验四个共激活指数。步态波形模式识别程序，以产生一个主要的模式，得分为每个肌肉部位和主题。混合模型方差分析（组肌肉）测试的主要模式score differentiations.Findings：一个显着的组效应被发现（P < 0.05）的所有四个共激活指数。主要模式一捕捉了整个站立阶段活动的幅度和一般形状。方差分析揭示了一个显着的（P < 0.05）组的肌肉相互作用的主要模式得分。在所有三个组之间和两个骨关节炎组之间的两个measures.Interpretation显着差异：共激活指数和主要模式确定，横向网站之间的差异发生在所有三个组与两个骨关节炎组之间的中间网站的差异。这些结果表明，肌肉协同活动的措施提供了额外的信息有关膝关节骨性关节炎的严重程度。(C)2009爱思唯尔有限公司保留所有权利。
Background: Increased muscle co-activation during gait has been identified as a neuromuscular alteration associated with knee osteoarthritis, however levels of co-activation among different osteoarthritis severity have not been established. The purpose of this study was to determine if differences in co-activation could be detected among asymptomatic controls, those with moderate and those with severe osteoarthritis using a co-activation index and a pattern recognition technique.Methods: Surface electromyograms from vastus lateralis and medialis, lateral and medial hamstring and gastrocnemius pairs were recorded from 63 asymptomatic, 59 moderate and 48 severe osteoarthritic subjects during self-selected walking. A co-activation index was calculated over the initial stance for four medial and lateral muscle pairs. The four co-activation indices were tested among groups using a one factor ANOVA (alpha = 0.05). Gait waveform pattern recognition procedures were applied to yield a principal pattern, scored for each muscle site and subject. A mixed model ANOVA (group-muscle) tested for principal pattern score differences.Findings: A significant group effect was found (P < 0.05) for all four co-activation indices. Principal pattern one captured the amplitude and general shape of activity throughout the entire stance phase. ANOVA revealed a significant (P < 0.05) group by muscle interaction for the principal pattern scores. Significant differences were found among all three groups and between the two osteoarthritic groups for both measures.Interpretation: The co-activation indices and principal patterns identified that lateral site differences occurred among all three groups with medial site differences between the two osteoarthritic groups. These findings suggest that measures of muscle co-activity provide additional information related to knee osteoarthritis severity. (C) 2009 Elsevier Ltd. All rights reserved.