Outcomes of hospitalisation for right heart failure in pulmonary arterial hypertension

Outcomes of hospitalisation for right heart failure in pulmonary arterial hypertension
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DOI:
10.1183/09031936.00148310
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发表时间:
2011-08-01
影响因子:
24.3
通讯作者:
Hassoun, P. M.
Hassoun, P. M.
中科院分区:
医学1区
文献类型:
--
作者:
Campo, A.;Mathai, S. C.;Hassoun, P. M.

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本研究的目的是检查肺动脉高压(PAH)患者住院的原因和结局。研究了2000年至2009年间90例PAH患者的205次连续住院。住院的主要原因是右心衰竭(RHF; 56%)、感染(16%)和出血性疾病(8%)。对于RHF患者,住院死亡率总体为14%,接受正性肌力药物治疗的患者为46%,入住重症监护室的患者为48%。院内死亡率的预测因素是结缔组织病(CTD)(OR 4.92)、收缩压< 100 mmHg(OR 4.32)和钠
The aim of this study was to examine the causes and outcomes of hospitalisation in patients with pulmonary arterial hypertension (PAH).205 consecutive hospitalisations occurring between 2000 and 2009 in 90 PAH patients were studied.The leading causes for hospitalisation were right heart failure (RHF; 56%), infection (16%) and bleeding disorders (8%). For patients with RHF, in-hospital mortality was 14% overall, 46% for patients receiving inotropes and 48% for those admitted to the intensive care unit. The predictors for in-hospital mortality were the presence of connective tissue disease (CTD) (OR 4.92), systolic blood pressure < 100 mmHg (OR 4.32) and Na