Resting-state EEG, impulsiveness, and personality in daily and nondaily smokers
Resting-state EEG, impulsiveness, and personality in daily and nondaily smokers
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DOI：
10.1016/j.clinph.2015.05.007
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发表时间：
2016-01-01
影响因子：
4.7
通讯作者：
O'Donnell, Brian F.
中科院分区：
文献类型：
--
作者：
Rass, Olga;Ahn, Woo-Young;O'Donnell, Brian F.
目的：静息EEG对尼古丁给药和戒烟的短暂急性效应敏感，但吸烟对EEG的慢性效应特征不明显。本研究测量了慢性吸烟者在非剥夺、非高峰状态下的静息EEG曲线，以测试吸烟行为和人格特征的差异是否影响药物-EEG响应。方法：从每日吸烟者（n = 22）、非每日吸烟者（n = 31）和非吸烟者（n = 30）中收集静息EEG、冲动和人格测量。与非每日吸烟者和非吸烟者相比，每日吸烟者的静息δ和α EEG功率降低，冲动（Barratt冲动量表）更高。每日和非每日吸烟者折扣延迟奖励更陡峭，报告较低的焦虑（NEO-FFI），并报告更大的去抑制和经验寻求（感觉寻求量表）比非吸烟者。非日常吸烟者报告更大的感觉hedonia比nonsmokers.Conclusions：改变休息脑电图功率在日常吸烟者表现出差异的神经信号，与更大的吸烟行为和依赖。虽然非日常吸烟者与日常吸烟者的一些特征，可以预测吸烟的开始和维护，他们不同的冲动和静息EEG power.Significance的措施：静息EEG在非剥夺慢性吸烟者提供了一个标准的比较，峰值和谷尼古丁状态，并可能作为尼古丁依赖，复发风险和恢复的生物标志物。(C)2015年国际临床神经生理学联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objectives: Resting EEG is sensitive to transient, acute effects of nicotine administration and abstinence, but the chronic effects of smoking on EEG are poorly characterized. This study measures the resting EEG profile of chronic smokers in a non-deprived, non-peak state to test whether differences in smoking behavior and personality traits affect pharmaco-EEG response.Methods: Resting EEG, impulsiveness, and personality measures were collected from daily smokers (n = 22), nondaily smokers (n = 31), and non-smokers (n = 30).Results: Daily smokers had reduced resting delta and alpha EEG power and higher impulsiveness (Barratt Impulsiveness Scale) compared to nondaily smokers and non-smokers. Both daily and nondaily smokers discounted delayed rewards more steeply, reported lower conscientiousness (NEO-FFI), and reported greater disinhibition and experience seeking (Sensation Seeking Scale) than non-smokers. Nondaily smokers reported greater sensory hedonia than nonsmokers.Conclusions: Altered resting EEG power in daily smokers demonstrates differences in neural signaling that correlated with greater smoking behavior and dependence. Although nondaily smokers share some characteristics with daily smokers that may predict smoking initiation and maintenance, they differ on measures of impulsiveness and resting EEG power.Significance: Resting EEG in non-deprived chronic smokers provides a standard for comparison to peak and trough nicotine states and may serve as a biomarker for nicotine dependence, relapse risk, and recovery. (C) 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.